Gadofluorine M enhanced MRI in experimental glioma: Superior and persistent intracellular tumor enhancement compared with conventional MRI
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چکیده
منابع مشابه
Gadofluorine M enhanced MRI reveals circumventricular organ involvement in CNS inflammation and facilitates occult lesion detection
Background: The central nervous system (CNS) may no longer be considered immune privileged but rather a site of selective immune activity. Although the bloodbrain barrier (BBB) covers most parts of the CNS, certain brain regions are devoid of it and are, therefore, in permanent contact to blood-born molecules and cells. These “exposed” areas include the choroid plexus and other small structures...
متن کاملQualitative and quantitative estimation of high risk atherosclerotic plaques in WHHL animals with Gadofluorine M – enhanced MRI at 3T
wall of a WHHL and a NZW control animal with prominent thickening of the intimal layer in WHHL animals Fig. 2 SNR Measurements before and 24h after injection of GdF demonstrate a significant enhancement of the aortic wall (SNR increase) in WHHL animals of the 100, 50 and 25 μmol group in contrast to the 12.5 μmol WHHL group and all NZW animals without significant SNR changes (p>0.05) Qualitativ...
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PURPOSE to explore the clinical value of 3.0T magnetic resonance (MR) imaging compared with computer-aided MR diagnosis (MR-CAD) in differential diagnosis of benign and malignant breast tumors. MATERIALS AND METHODS MRI method and MR-CAD method was used in the diagnosis of a total of 93 breast lesions of 78 patients, based on the morphological and time-intensity-curve (TIC) analysis. The accu...
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AIM To evaluate the efficacy and efficiency of three-dimensional (3D) fast spin-echo (FSE) with variable flip angle ("CUBE") magnetic resonance imaging (MRI) in knee imaging as compared with conventional MRI. MATERIALS AND METHODS Twenty-nine patients (single knee) with joint injuries of varying degrees were enrolled in this study between January, 2011 and December, 2011. All patients underwe...
متن کاملGadofluorine M enhancement allows more sensitive detection of inflammatory CNS lesions than T2-w imaging: a quantitative MRI study.
Magnetic resonance imaging plays a pivotal role in the diagnosis and treatment monitoring of multiple sclerosis. Currently available magnetic resonance-techniques only partly reflect the extent of tissue inflammation and damage. In the present study, application of the experimental magnetic resonance-contrast agent Gadofluorine M significantly increased the sensitivity of lesion detection in my...
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ژورنال
عنوان ژورنال: Journal of Magnetic Resonance Imaging
سال: 2011
ISSN: 1053-1807
DOI: 10.1002/jmri.22869